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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Player | From-To | W | L | Pct | ERA | G | GS | CG | SHO | SV | IP | H | ER | HR | BB | SO |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Tim Eaton | 2048-2051 | 0 | 0 | .000 | 9.00 | 2 | 0 | 0 | 0 | 0 | 2.0 | 3 | 2 | 0 | 1 | 1 |
| Enzo Echevería | 2044-2044 | 0 | 6 | .000 | 6.50 | 11 | 11 | 0 | 0 | 0 | 44.1 | 49 | 32 | 4 | 32 | 56 |
| Fred Edmonds | 2025-2025 | 1 | 0 | 1.000 | 0.00 | 1 | 1 | 0 | 0 | 0 | 6.0 | 3 | 0 | 0 | 1 | 7 |
| Fernão Ega | 2048-2049 | 9 | 9 | .500 | 4.86 | 30 | 30 | 0 | 0 | 0 | 153.2 | 154 | 83 | 21 | 38 | 128 |
| Stephen Elam | 2030-2030 | 4 | 3 | .571 | 4.23 | 13 | 13 | 0 | 0 | 0 | 61.2 | 59 | 29 | 2 | 27 | 60 |
| Jerry Elder | 2041-2041 | 8 | 5 | .615 | 3.63 | 15 | 15 | 2 | 1 | 0 | 111.2 | 108 | 45 | 10 | 44 | 135 |
| José Elías | 2045-2045 | 0 | 4 | .000 | 5.26 | 27 | 0 | 0 | 0 | 7 | 25.2 | 30 | 15 | 3 | 24 | 37 |
| Olezka Elizarov | 2032-2034 | 0 | 0 | .000 | 0.00 | 2 | 0 | 0 | 0 | 0 | 3.0 | 1 | 0 | 0 | 0 | 4 |
| Kel Elizondo | 2045-2048 | 4 | 3 | .571 | 4.50 | 16 | 16 | 0 | 0 | 0 | 80.0 | 85 | 40 | 5 | 33 | 77 |
| Robert Elliott | 2049-2050 | 3 | 7 | .300 | 4.56 | 45 | 0 | 0 | 0 | 22 | 47.1 | 36 | 24 | 2 | 59 | 64 |
| George Ellis | 2034-2034 | 3 | 0 | 1.000 | 2.20 | 7 | 0 | 0 | 0 | 0 | 16.1 | 9 | 4 | 0 | 8 | 27 |
| Steven Ellis | 2050-2051 | 6 | 3 | .667 | 3.71 | 52 | 0 | 0 | 0 | 2 | 119.0 | 120 | 49 | 9 | 43 | 137 |
| Steve Emery | 2040-2040 | 0 | 1 | .000 | 2.73 | 23 | 0 | 0 | 0 | 14 | 26.1 | 18 | 8 | 2 | 15 | 55 |
| Jesús Encarnación | 2026-2027 | 1 | 1 | .500 | 1.64 | 24 | 0 | 0 | 0 | 11 | 22.0 | 10 | 4 | 0 | 15 | 27 |
| Víctor Encarnación | 2049-2050 | 6 | 6 | .500 | 4.95 | 30 | 12 | 1 | 1 | 2 | 96.1 | 90 | 53 | 4 | 72 | 109 |
| Ryoichi Endo | 2046-2047 | 3 | 10 | .231 | 5.99 | 17 | 17 | 1 | 0 | 0 | 88.2 | 117 | 59 | 9 | 44 | 71 |
| Nacho Enríquez | 2046-2049 | 5 | 4 | .556 | 3.95 | 64 | 0 | 0 | 0 | 1 | 164.0 | 163 | 72 | 17 | 59 | 194 |
| Steve Ervin | 2037-2037 | 8 | 2 | .800 | 3.92 | 16 | 16 | 1 | 1 | 0 | 103.1 | 99 | 45 | 4 | 55 | 118 |
| Roberto Escobar | 2047-2048 | 7 | 9 | .438 | 5.11 | 23 | 23 | 0 | 0 | 0 | 105.2 | 108 | 60 | 4 | 67 | 113 |
| Francisco Escobedo | 2045-2046 | 7 | 1 | .875 | 2.64 | 12 | 12 | 0 | 0 | 0 | 61.1 | 52 | 18 | 3 | 31 | 62 |
| César Esparza | 2046-2047 | 3 | 4 | .429 | 4.95 | 8 | 8 | 0 | 0 | 0 | 43.2 | 39 | 24 | 6 | 19 | 37 |
| Ricardo Esparza | 2046-2046 | 0 | 4 | .000 | 3.57 | 16 | 0 | 0 | 0 | 0 | 22.2 | 24 | 9 | 2 | 8 | 28 |
| Juan Espinosa | 2046-2046 | 3 | 1 | .750 | 2.37 | 28 | 0 | 0 | 0 | 5 | 30.1 | 21 | 8 | 1 | 5 | 40 |
| Jesús Estrada | 2045-2051 | 24 | 9 | .727 | 2.61 | 53 | 50 | 4 | 3 | 0 | 304.0 | 214 | 88 | 28 | 130 | 389 |
| Pedro Estrada | 2028-2028 | 0 | 0 | .000 | 0.00 | 3 | 0 | 0 | 0 | 0 | 3.0 | 1 | 0 | 0 | 1 | 2 |
| Robert Estrada | 2032-2032 | 2 | 3 | .400 | 5.58 | 7 | 7 | 0 | 0 | 0 | 30.2 | 29 | 19 | 3 | 19 | 36 |
| Albert Evans | 2025-2026 | 6 | 5 | .545 | 3.20 | 64 | 0 | 0 | 0 | 29 | 76.0 | 61 | 27 | 9 | 46 | 94 |
| Arthur Evans | 2039-2039 | 8 | 8 | .500 | 3.66 | 25 | 24 | 1 | 0 | 0 | 142.2 | 130 | 58 | 14 | 65 | 157 |
| Bill Evans | 2051-2051 | 0 | 2 | .000 | 10.38 | 4 | 4 | 0 | 0 | 0 | 13.0 | 18 | 15 | 2 | 9 | 13 |
